Title page Deep Brain Stimulation in Parkinsonian patients – Ethical evaluation of stimulation-induced personality alterations
نویسندگان
چکیده
110 words) Deep brain stimulation of the subthalamic nucleus (STN DBS) has become an important option for treatment-resistant Parkinson’s disease. Although the beneficial effects of STN DBS on motor functions have been well described, complex affective and behavioral sequelae moved only recently in the focus of the medical and ethical discussion. We classify potential side-effects of STN DBS found in the scientific literature along the dimensions measurement complexity and individual life-impact, identifying side-effects of high ethical impact where compelling data is missing. Based on this analysis, we discuss the ethical consequences of complex side-effects resulting from STN DBS and outline guidelines that should be integrated in the therapeutic setting of STN DBS.
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